University of Florida Scientists to Study "Bath Salts"

Pat first wrote about the scary new designer stimulant known as "bath salts" in March 2011, and did a follow up in November 2011.  I then chronicled the nightmare story of our client Miles, who checked in addicted to bath salts in April of this year and almost four weeks later suffered what appeared to be a rebound, with a follow up about the impact that rebound had on Miles.    My reports caught the attention of many including Dr. Charles Parker who posted a very interesting comment to this article,  and then our own advisor on neuroscience Dr. Kenneth Blum, PhD.  bathsalts-epidemic.jpeg

We like to be of service to the addiction community, so I was pleased to learn recently that Dr. Blum had proposed to scientists at the University of Florida’s College of Medicine (Gainesville), in the Department of Psychiatry and Mcknight Brain Institute Study, that they study the delayed onset effects of  bath salts.  Dr. Blum just let me know that he and his colleagues, including Drs. Mark Gold MD and Febo Marcelo PhD, are embarking on a rodent study developed by Dr. Kevin Wang PhD and associates concerning "Bath Salts as a Potential Inducer of Neuroinflammation."  

The Florida team under the direction of Dr. Marcelo will also explore the effects of bath salts on brain reward circuitry using fMRI in rodent models as well.

This is no easy task because the effects of bath salts are so egregious – some people ingest them and end up murdering others – that the FDA has at least temporarily classified the main ingredients as a Schedule I narcotic, making them hard for the Florida team of scientists  to access.  We are rooting for all of you at the University of Florida whose research we hope will help to enlighten the health insurance providers (Anthem Blue Cross thought it was safe for Miles to live in the community and commute to treatment, despite intense cravings for bath salts) and doctors everywhere.

In the meantime we received this very helpful infographic about bath salts from  the folks at edrugrehab along with permission to share with all of our readers.  You can download it for free.

 

 

Bath Salts Part 2: Miles returns to his former self

On April 16, 2012 we wrote about Miles, his use of the very dangerous designer stimulant "bath salts," and the manic behavior that occured weeks after he stopped using them, suggesting the chemicals in "bath salts" have a rebound effect.

Here is the end of the story, as told by his mother.Man in the Fog.jpg

"Miles ended up getting kicked out of the next rehab (NOTE:  a very tough behavior modification treatment center in the San Fernando Valley).  He stayed out in their lobby for hours, trying to get someone to pick him up.  It took everything we had inside as a family to say no, but we all did and so did his long-time girlfriend.  He was cold, hungry and out on the street in a very bad area.  The treatment  center staff gave him a sack lunch and let him keep his belongings in their storage room, but he had to leave when they closed the lobby.  He went to a meeting and got a "couch commitment" for the night.

"My husband picked him up the next morning to take him to see his probation officer.   When he picked him up, Miles was completely subdued and grateful.  My husband said they had the best day together.  He brought him to our home  and made arrangements for Miles to stay in a hotel down the street from probation for one night, then they got Miles into a sober living house from Thursday thru Tuesday, at which point Miles was scheduled to go to court for a review.  Interestingly, Miles stayed in the hotel room all night by himself, ate pizza and watched hockey on TV (we know because he called his dad and brother throughout the entire game as they were watching it here).  He walked to the probation office the next morning and was instructed to report there each morning until court.  He had to attend double and triple meetings until court.  After that meeting with probation he took a cab to the sober living house with his belongings and stayed there as instructed.  He walked everywhere he needed to go for the next several days and went to lots of meetings. He didn't ask for his car back, which we would have refused anyway but we didn't have to.

"After he left [the Valley behavior modification rehab] with 2 big bags of meds, the only thing he took was Gabapentin and Seroquel at night for anxiety and sleep!  My husband picked him up Sunday morning and brought him to offload most of his clothes and shoes and he gave me his bags of meds and said he didn't need them!  He went to church with us, did laundry, watched hockey with his dad and brother and we had a barbeque that evening with all of the kids and grandkids.  Miles was like his old self and happy and compliant.  My husband took him back to the sober living house that evening and he went to court on Tuesday. 

"He was drug tested at probation prior to his review and they tested him for everything they could and they all came back negative.  Then he went to court and he was given a "strike" for hopping from place to place and not calling his probation officer to let them know where he was going.  If only they knew how crazy and out of control he was during that month, they would know why he never called.  They court-ordered him to the Salvation Army for 6 months.   He accepted the fact that he would go and got himself on a waiting list.

"We took Miles to the Salvation Army yesterday morning.  We checked him in and we will not have contact with him for about 30 days unless they feel he has information we need to know.  He can't have his cell phone for 6 months and he will work 5 days a week for $1 a day.  He could only bring underwear and toiletries.  He was ok on the way down and even though 6 months is a long time, he said he is sick of the "lifestyle" and "too much drama".  While he was at the sober living he spent a day with a sober friend and 2 sober girls and had a blast and that seemed to make such an impression, that he could have a fun day clean and sober and be happy.  Miles faces jail and/or prison if he leaves or gets kicked out of the Salvation Army, so we are hoping and praying his mindset stays as it has been the past week-committed, surrendered and focused on his recovery.

"I may have told you more than you wanted to know, but it has been such a ride and I am grateful that thus far it hasn't ended in our planning a funeral for Miles.  I don't understand how and why he went from utter chaos and craziness to a calm, happy young man, but I feel that I had my "real son" back when he came back from Valley.  It did send a strong message when we all turned our backs on him and he has since lost his girlfriend of the past 5 years altogether now.  She won't return his calls and messages and we support her in moving on without Miles.  We believe she has had enough and is also a distraction for Miles in his recovery.  He is insecure without her but is beginning to see that this is life and it's time for him to deal with it.

"I hope the 'more to come' is a good ending to the story of 'Miles'.  I still wonder if the 2 months of out of control, manicky, crazy behavior has anything to do with the bath salts.  I have never seen Miles quite like that and I hope I never do again. 

"Bath Salts:" A Designer Stimulant That Rebounds???

When Pat first reported on the new “bath salt” epidemic, it didn’t really click.    Even her “bath salt” update had me scratching my head. 

Then the manager of our sober living found Ann (not her real name), a young resident, wandering around the front yard speaking to the bushes.  Her co-residents said she had ordered “bath salts” over the internet.  She seemed fine several days later, but in only a matter of weeks the manager told me she had been admitted to the UCLA’s Neuropsychiatric Institute where she reportedly remained for two weeks strapped to her bed.bath salts 2.jpg

A month ago I got a call from a Southern California college town.  Miles (not his real name)  -- bright, articulate and charming -- said he needed help, the type that an outpatient program could not provide.  He was ready to “do the work” in a safe, secure setting rather than tangle with the law and “lose everything.”

From the vast amounts of drugs Miles, 21, reported having taken since he was 15, he was one hard core addict.  He had managed 6 months of sobriety in 2010.  Then “all hell broke loose” and he was arrested for possession of Xanax, cocaine, and marijuana, as well as intent to sell marijuana  In jail he stayed high on suboxone which was mailed to him glued to the flap of the envelope (Pat wrote about this last December).

One day a friend introduced him to “bath salts,” a designer stimulant which mimics the high of cocaine and methamphetamine.  Note to Normies (non addicts):  These are not the lavender scented crystals on sale at your local drug store.  These are possibly the most dangerous drug on the market today, produced in clandestine labs, sold online or in smoke and head shops.  

“Bath Salts” are usually made from MDPV or methylenedioxypyrovalerone, a psychoactive drug, though newer derivatives are being made by illegal street chemists.   Dr. Zane Horowitz, MD, an emergency room physician and medical director of the Oregon Poison Center described for WebMD the side effects he has observed: "agitation, paranoia, hallucinations, chest pain, sucide...high blood pressure and increased pulse."  He added:  There's something more causing these other extreme effects." newscaster announcing bath salt ban.jpg

Most often the label on "bath salts" attempts to skirt legality by stating the product is not for human consumption (which is not a deterrent to young adults who anyway smoke, snort or inject them). 

In September 2011 the Drug Enforcement Administration used emergency scheduling authority to temporarily control MDPV (along with Mephedrone and Methylone) by classifying it as a Schedule I Substance.

Schedule I status is reserved for those substances with such a high potential for abuse they cannot be used for treatment in the United States.  Until next September, and possibly forever, possession or sale of MPDV is illegal.. 

Last November California followed the lead of at least 28 states and banned “bath salts.” 

Nonetheless, there is still a single source in Miles’ college town – a smoke shop that also sells salvia (an herb with hallucinogenic properties) and spice (an herbal alternative to marijuana) .  Miles said the “bath salts” he inhaled are called “Bubbles” and come in a “ready to snort”  container with a twist off cap.  The powder itself “looks a lot like Splenda.” 

The “bath salt” containers are kept locked in a glass showcase.  The store's only clerk has the key.  Miles said each container cost $35.00 cash and is labeled:  “Not for human consumption- does not contain MDPV.”  

(Dr. Charles Sophy, a favorite Malibu Beach Recovery Center psychiatrist warned:  “Consumers should not be fooled.  Bath Salt ingredients, no matter what disguise they may come in, still remain a potential substance for abuse.  The abuse potential and its aftermath can be very harmful.” )

Miles described the “bath salts” as rendering the “best” high ever.  10 times better than a meth, he said.  And unlike all the other drugs he has ever snorted/injected/smoked, it was the bath salts which took him down.  Each container kept Miles “loaded” for up to 8 hours.  By the time he called Malibu Beach Recovery Center he could no longer go more than an hour without bath salts.  It had become a $100/day habit that “had me by the throat.” 

For Miles the side effects included delusions, insomnia ( he reported having had no more than 6 hours in twelve days), shortness of breath, restless leg syndrome, anxiety, and  lack of appetite.   

“When I hugged him,” said his mom, “he had lost so much weight I could feel all the ribs, all the bones.”

Twenty four days after entering treatment Miles relapsed.  Somehow he had obtained Xanax. Relapse while in treatment is a very rare occurrence at Malibu Beach Recovery Center.  We immediately helped him transfer to a different treatment program.  Two days later his mom emailed:  “He sounds terrible to me.  This morning he woke up in excruciating pain in both hips and could not move.  He needed assistance to get out of bed….I am truly afraid we will lose him.”

The other treatment program then discharged him.  They reported cognitive memory issues and said he was out of control with drug seeking and had no concern for consequences. 

He was checked into a psych ward.   When his insurance ordered him stepped down to a lower level of care, Miles panicked and wanted to go back to the hospital.

I heard from Miles’ dad this morning.  He wrote:  “Unfortunately, the saga continues...” 

Two days earlier Miles had been rushed to the ER.

“The clinical team at his rehab was sure he OD'd on something as he was nodding out during the morning meeting,” wrote his Dad. “ Miles insisted he didn't take anything more than the treatment center gave him.  He walked all the way from the hospital back to the treatment center in flip flops because he needed his meds.  His feet were black, he had a deep cut on his ankle, his foot and ankle were red and swollen and he was limping.  They wouldn't let him on the premises and said they would have to call the cops if he caused a scene.  He paced back and forth across the street and called them and us, begging for a dose of his meds.   

“I was horrified when we picked him up.  He looked like a homeless man I barely recognized, not the handsome young guy with the big smile and bright eyes.  He was dirty, ragged and nodding out when talking to us, and all he had was the medication they prescribed.” 

Miles’ dad is inclined to believe that even if Miles was able to access some street drugs while in treatment, or was able to hoard enough of his prescribed medications to take alot at one time, the amounts available could not have triggered the extreme behavior Miles is exhibiting, all of which mimic the DEA's description of the worst "bath salts" side effects:  impaired perception, reduced motor control, disorientation, extreme paranoia and violent episodes.

Which led me to call Dr. Kenneth Blum and ask him if bath salts have a rebound effect.

Here is what he said:  "There must be additional research done to determine whether after ingesting bath salts a severe neuopsychological rebound can result.    This abused substance may be  more dangerous than even crystal meth and all legal authorities must enforce laws against its sale in the entire United States of America.  Our professional and scientific community must declare "war" against its use to save our precious next generation from its profound neurotoxicity."   

 

If any of our readers have experienced a rebound from "bath salts", or know about someone who has, please post a comment.  Your information might help save Miles' life, or the life of someone else.

Checking In -- Four Loko, Bath Salts, and College Drinking

Four LokoFour Loko.jpg

 

Remember the drink with the flashy packaging that is so popular with college students? I first wrote about Four Loko last November in Juiced, in More Ways Than One (Wow,has it really been almost a year?) This drink is particularly harmful because the caffeine in it seems to make people oblivious to how inebriated they’re getting from the alcohol. New York, New Jersey, and Michigan were a few states that banned sales of the drinks around that time.

Now the makers of Four Loko have agreed to label the amount of alcohol in their product: one can contains as much as four or five cans of beer. (This was after they were pressured from the Federal Trade Commission.) I could not find a current list of states banning the beverate

 

Bath Saltsbath-salts-get-you-high.jpg

Bath salts are in the news again, too. I wrote about the problem in March, here: Bath Salts--Not so Soothing. Bath salts are not at all what the name implies—they’re deadly, and unfortunately, they’re still a top recreational drug. Although 28 states have banned them, they’re still wreaking havoc, according to an article in The New York Times. According to this latest article, they contain “manmade chemicals like mephedrone and methylenedioxypyrovalerone, or MDPV, also known as substituted cathinones. Both drugs are related to khat, an organic stimulant found in Arab and East African countries that is illegal in the United States.”

 

College Students and Drinking Thumbnail image for alcoholic = silouette and bottle.jpg

I know I just wrote about substance abuse on college campuses in    But this subject is constantly in the news. As if to prove my point, ABC News recently featured a segment that caught my attention. If you’re on Facebook, how many times have you seen young people posting details about their debauchery? Researchers at the University of Wisconsin-Madison found that college students who post about their drinking may be clinically at risk for alcohol abuse. The researchers analyzed profiles and then had these students complete questionnaires about their drinking. Not surprisingly, more than half of students, who posted about blacking out, drinking while driving, or drinking alone, were found to be at risk for alcoholism. One outcome: The lesson that it’s important to listen to how students talk about their drinking.

 

Bath Salts--Not so Soothing

Just when you think there’s not one other substance people could possibly take to get high, bath salts appear. Who would have thought it? There’s been a tragedy in my state thanks to this seemingly innocuous product. A college student killed his girlfriend, and his mother attributes it to the bath salts. It boggles the mind.

The crime was reported in the Asbury Park Press, my local paper, and on New York TV last week. A 22-year-old has had her life cut short, and New Jersey joins other states experiencing violent incidents attributed to bath salts. The woman’s long-time boyfriend, William Parisio, suffers from bipolar disorder and reportedly had problems with alcohol and other drugs. It’s believed he snorted, smoked, ate, or injected the bathbath salts.jpg salts, which the article said can cause hallucinations, delusions, and agitation, similar to the effects caused cocaine, LSD and other drugs. A Drug Enforcement Administration spokesperson said that the salts also cause insomnia and make one quick to anger.

Appearing on TV, the woman’s heart-broken father said that he had warned his daughter Parisio wasn’t right for her, but she thought she could help him.  She’s not the first girlfriend who has mistakenly thought that about a boyfriend who has problems requiring professional help.

Two NJ lawmakers have stepped up to try and avert further incidents in my state. They’ve suggested legislation to make it a third degree crime and result in a stiff prison sentence and fine for manufacturing, selling, or even possessing bath salts – “products containing mephedrone or methylenedioxypyrovale­rone, also known as MDPV,” according to the newspaper article.

An expert’s thoughts on bath salts made me shudder: “If you take the very worst of some of the other drugs — LSD and Ecstasy with their hallucinogenic properties, PCP with extreme agitation, superhuman strength and combativeness, as well as the stimulant properties of cocaine and meth — if you take all the worst of those and put them all together, this is what you get,” said Mark Ryan, director of the Louisiana Poison Center, in one recent published report. “It’s ugly.”

Three states—North Dakota, Louisiana, and Florida—have banned bath salts. However, you can still buy them, under names like Ivory Wave or Vanilla Sky, at conven­ience stores in other states.