The Good News: F.D.A. Shoots Down OxyContin Generics The Bad News: Pharma Co. Hikes Price on Naloxone

The Food and Drug Administration refused to approve generic versions of OxyContin, which is very good news. Experts agree that this will help stop the epidemic of prescription pill abuse, and the news indicates that the F.D.A. is doing what it can to help.opiates.jpg

Purdue Pharma gets a bad name as the manufacturer of the painkiller that “symbolized a decade-long epidemic of prescription drug abuse,” according to The New York Times. However, the company started manufacturing a different version in 2010 that was “less prone to tampering.” (It turned to jelly when people tried to crush it for snorting or injecting.)

Purdue Pharma’s patent was expiring when this ruling came down, which is why this was such good news. It means that the companies that want to manufacture generic versions of the drug won’t be able to contribute to the drug abuse epidemic. If they want to sell the drug at all, these companies will have to come up with formulations that are more difficult to tamper with, like Purdue Pharma did.

A Medpage “breaking news” email noted that there are new labeling requirements for the drug; specifically, that it "has physical and chemical properties that are expected to make abuse via injection difficult and to reduce abuse via the intranasal route." This effectively thwarts companies hoping to sell generics that don’t comply

The bad news for people who really need OxyContin for medicinal purposes is that the price of OxyCodone has risen since 2010.  However, if other manufacturers come up with tamper-proof generics, that could keep a lid on prices and even help reduce them.

Endo Pharmaceuticals has also requested that the F.D.A not approve generics for their Opana, another narcotic pain killer of similar “painkilling strength.” This company, too, has come up with a formulation that is harder to tamper with.

However, the article raises the question about the drug manufacturers’ motives, whether they only really care about profits, saying “In court papers filed in response to a lawsuit filed by Endo, the F.D.A. described the company’s action as a ‘thinly veiled attempt to maintain its market share and block generic competition.’”

There’s other news about the price of a drug that, rather than contributes to prescription pill abuse, saves lives. I first wrote about Naloxone over a year ago. If you remember, this medication can help revive a person who overdoses on an opiate like heroin, and there are programs that dispense the drug for free. Hospira is currently the only company still manufacturing the medication, and Alternet noted that the price has skyrocketed by $1,100 since 2008.

The director of a Chicago program called the company in in 2008 to ask for a break, he was able to get a reduced price. Thankfully, Hospira is working with other nonprofits to offer more reasonable prices. Addiction writer Maia Szalavitz noted in another Alternet article that some programs have already folded. Shockingly, Hospira stands to make $20 million from the drug. Naloxone is injected and expensive to make, so there’s little incentive for other companies to jump to market it.

The F.D.A. is considering making Naloxene available over the counter (will that make it less expensive?), but nothing has happened yet. 

 

A Pain-Drug Champion Changes His Mind About Opioids

BI front entrance.pngPharmaceutical companies are often accused of contributing to American’s overusing medications because of the companies’ ubiquitous advertising. But in a Wall Street Journal article, a 1990’s advocate of pain medication has done a 180-degree turn in his thinking, perhaps taking a bit of the blame for the ensuing prescription drug abuse epidemic.  

Dr. Russell Portenoy, a pain management specialist at Beth Israel Medical Center in NY (in fact, he’s department chair), initially said that painkillers like Percocet, Vicodin, and OxyContin—all derived from the opium poppy—could help people with chronic pain, and the drugs grew in popularity. But now he says he went too far and he didn’t warn people enough about the risk of becoming addicted. Sounding somewhat guilty, he says "We didn't know then what we know now."

The drugs are notoriously more addictive than previously thought, and not always the best solution for long-term pain. Unfortunately, not all doctors know that the tide has turned among early proponents of using these drugs for pain management!

Initially, Portenoy was a key promoter of opioids beyond being used mostly for cancer pain, and he actually said, along with some followers, that there were few overdoses and less than 1% of users become addicted. He wasn’t just kidding when he said recently that if only we’d known then what we know now.

It’s heartening to hear him come clean about his possible part in the current drug epidemic. He didn’t have to speak the truth. But then he mentions some good that came of his promotion, attributing his mother’s relief from arthritis pain to her 15 years of hydrocodone use.  It’s true that these meds help many people in the short-term and that not everyone becomes addicted, even with long-term use. Plus, pain is real and people in pain deserve relief.

But it’s frightening when one person, or a small group of people, wield so much power. People look up to their medical professionals and rely on them. Thank goodness for the movement in which patients are persuaded to take a more active role in their medical care and are more comfortable questioning their doctors.

It’s also frightening to learn what the drug companies did after doctors jumped on the bandwagon ofThumbnail image for Oxycontin.gifdangerously prescribing opioids. The article says that “In 1996, Purdue Pharma LP released OxyContin, a form of oxycodone in a patented, time-release form, and rivals followed suit.”  It seems that they paid the price, though. “In 2007, Purdue Pharma and three executives pleaded guilty to ‘misbranding’ of the drug as less addictive and less subject to abuse than other pain medicines and paid $635 million in fines.”

Portenoy was also president of the American Pain Foundation in the 1990s; thus, he had a perch from which to spread his message. Also, he had relationships with over 12 companies that produce opioids, and justifies it by saying, and I paraphrase, they benefit his educational and research missions, and partially, his pocketbook – “without producing in me any tendency to engage in undue influence or misinformation.”  

It’s hard to believe this stuff went on. This story is a blemish on the history of pain management.




 

Congresswoman Mary Bono Mack Speaks Out Against Prescription Pill Abuse

No matter what side of the political fence you’re on, you have to hand it to Mary Bono Mack for taking a stand against prescription pill abuse. The Republican representative from California is heading a commerce panel for the Energy and Commerce Committee to raise awareness of the problembono_mack_home-200x300.jpg

On April 4, Bono Mack, the widow of singer turned Congressman Sonny Bonowho entered politics after his death, introduced legislation that would ensure that no one can get drugs containing Oxycodone for other than the intended use – to reduce severe pain. The legislation is called the Stop Abuse Act of 2011 (H.R. 1316) and she has garnered support from several of her colleagues in Congress. It’s a cause that’s personal for the Congresswoman but she’s well aware it affects the whole country. Her son Chesare became addicted to Oxycontin, and the two have seen several friends get hooked, too. 

It’s hoped that the legislation will stop Oxycontin pills from being so widely marketed. For one thing, the law, if passed, will help thwart the pill mills that are rampant in Florida.  

Our representatives in Congress aren’t the only Americans wanting to step up. Awhile ago Taylor Armstrong posted about April Rovero, who founded the National Coalition Against Prescription Drug Abuse, after her son died of an overdose from prescription pills. This is a bipartisan issue.

 

 

One in Eight Big Apple Residents Prescribed Oxycontin

New York City owns a disturbing statistic: prescriptions for oxycodone have doubled in the last three years, according to one of its narcotics prosecutors. The Wall Street Journal article referring to it as “the city’s prescription drug abuse epidemic” was so matter-of-fact it was scary. The article said that the figures equate “to one prescription for every eight people” in the city. I’m reminded of how The New York Times posted the number of casualties in a recent military conflict every day to illustrate the rising toll. The articles about oxycodone have the same effect—chillinoxycontin2.jpgg.

Unfortunately, the problem has a ripple effect. Less than an hour from New York City, in Newark, NJ, police uncovered an oxycodone ring whose members included a doctor and a retired policeman. Twelve people. The Wall Street Journal article appeared on March 16; the NorthJersey.com article about Newark appeared on March 24.  The culprits face up to 20 years in prison.

I love the statement in the article on the NorthJersey.com site from a government staffer: “Doctors who illegally  prescribe  are often the first link in a chain of addiction and suffering,” said U.S. Attorney Paul J. Fishman. Horrific.  But they’re not the last.

The police had this group under surveillance for a year. You wonder how these criminals approached each other. How did they know who would be interested  in joining them? How  many people did they reach ? How many people who are cut off will just find another source? Will some go for treatment?

Both these states are known for so many good things.  The prescription pill epidemic is not one of them.

SB 1071 (CURES) update: Purdue Pharma Offers $1 Million to Help Fund Florida's Prescription Drug Monitoring Program

According to a recent press release Purdue Pharma, the pharmaceutical company that manufactures OxyContin, will provide a $1 million grant to support the operation of a prescription drug monitoring program ("PDMP") in the state of Florida, to help combat the illegal diversion and abuse of prescription medications.  The Company also announced a $1 million grant to the National Association of Boards of Pharmacy to support that organization's program to help State PDMPs detect "doctor shopping" across state lines.

What about California?

On May 5, 2010 I took a group of alumni to Sacramento to lobby for passage of SB 1071, a bill aimed at providing continued funding for CURES, California’s online real time PDMP. The State of California was broke at the time  (still is) and was unable to continue underwriting CURES although it was being used by more and more doctors to quickly determine if a patient was doctor shopping or pharmacy hopping for drugs like oxycontin, vicodin, valium, fentanyl, and morphine. Senator DeSaulnier photo.jpg

At the urging of his constituent Bob Pack, whose children were killed by a woman driving under the influence of multiple vicodin prescriptions, State Senator Mark DeSaulnier (D-Concord) undertook the responsiblity of finding ongoing funding for CURES. Pack, a computer company owner, had already helped the Department of Justice modernize California's antiquated system.  

Senator DeSaulnier staff, working with Pack and the Office of Attorney General (now Governor) Jerry Brown, determined that the most likely sources of underwriting were the pharmaceutical companies that manufacture these highly addictive narcotics.  SB 1071 called for a tax of $0.0025 for each Schedule II, III and IV narcotic prescription filled in California -- less than 25 cents a prescription.

I spoke briefly during the hearing with Frederick H. Noteware, a lobbyist who represents the pharmaceutical industry in Sacramento. He had just testified against passage of the SB 1071.  He thought the purpose was “worthy,” but he insisted that the pharmaceutical companies which manufacture narcotics were not responsible for the irresponsiblity of doctors who over prescribe, and wrongly prescribe.  We did not agree, and neither did the many parents who testified that day about the children they had lost to OxyContin.

As Senator DeSaulnier said at the hearing:  “I differ with the pharmaceutical companies.  When they make a profit and there is a mitigation for the profit, they should participate.”

SB 1071 did not get enough "yes" votes from Senate Health Committee members to move to the Finance Committee.  Senator DeSaulnier found some interim funding to keep the database alive and continued his campaign to find permanent funding.  

On July 28, 2010 the Contra Costa Times, a newspaper in Senator DeSaulnier's district, published an article about OxyContin entitled "A Silent, Growing Problem Among Youths." Journalist John Simerman quoted an email from Libby Holman, a spokeswoman for Purdue Pharma.  She wrote that while the company opposed SB 1071 it supports "appropriately designed" prescription monitoring programs.  "Prescription drug abuse is a serious public health concern and Purdue is taking an active role in being a part of the solution to the problem."

Several days later, on August 3, 2010 Senator DeSaulnier wrote to John H. Stewart, President and CEO of Purdue Pharma, requesting that Purdue take an immediate and productive role to combat the problem of abuse and addiction to prescription painkillers in California.  Oxycontin.gif

Senator DeSaulnier then met with Robert McElderry, the Regional Director of Purdue.  According to Indira MacDonald, the Senator’s legislative aide: “The Regional Director vowed to be supportive of the Senator’s efforts, but not the way he went about it in SB 1071.  In the meeting, Purdue would not commit funding without California first meeting higher marks in terms of what funding practitioners and pharmacist contribute to the CURES.”

On March 14, 2011, after Purdue Pharma officially announced they would provide funding to Florida’s online data base, Senator DeSaulnier again wrote to the President and CEO of Purdue Pharma.

'I write to continue our dialogue regarding your company’s commitment and support of California’s prescription drug monitoring program... As we begin a new legislative session, I am eager to work with your company in responding to the problem of abuse and addiction to prescription painkillers.

'While the launch of our state PDMP is a constructive step forward, we now face an enormous challenge to register more users. The sheer number of California practitioners and pharmacists eligible to prescribe and dispense prescription controlled substances makes this outreach effort an enormous one. Before even having the capability to register all potential users of the PDMP, we must first enhance the system’s capability (this includes: hardware, software, etc.) to withstand the volume of registered users and hits (requests for patient information), as well as provide the necessary staff to appropriately manage this registration process and upkeep the system.

'I applaud your company’s responsible economic support of the National All Schedules Prescription Electronic Reporting Program (NASPER) under the Department of Health and Human Services to support states in establishing PDMPs as well as your company’s recent grant award to combat the illegal diversion and abuse of prescription medications in the state of Florida.

'I would like to ask for your assistance to the California Department of Justice office of the Attorney General in providing CURES with the necessary resources to enhance the capacity of our PDMP as this is the obstacle we currently face to prevent and detect the diversion and abuse of pharmaceutical controlled substances. Without additional funds, achieving full usage of the PDMP cannot be met and therefore, our ability to fully protect the public is hindered.

'Without your company’s direct reinvestment into states’ efforts to combat the crisis before us, being an active part of the solution, we cannot win this fight. As a longtime business owner, I have always held that financial success should come by way of responsible business practices. Consumer’s safety and trust is greatest when businesses meet their moral obligations to mitigate negative effects. As a product steward, your reinvestment is appropriate and necessary. With your alliance and a public/private partnership we can make improvements to the responsible market of prescription controlled substances, ensure patient privacy and access to appropriate medical care, while also detecting the illegal diversion of controlled substances in order to save lives.

'I look forward to working with you and your company to support the operation, expansion and awareness of prescription drug monitoring programs. In particular, I look forward to hearing from you in regards to funding the CURES’s PDMP for the systems sustainability enhancement to increase registration and usage."

Great letter.  No response as yet from Purdue Pharma. 

Footnote:  Readers will hopefully remember the “Addiction by Prescription” article I wrote for this blog on October 02, 2010 article. 

It was about Bill, 22, a resident of Simi Valley, one of L.A.’s bedroom communities whose young people are being decimated by addiction to prescription drugs, especially OxyContin.  Bill’s mom had committed to walking from one side of Simi Valley to the other 40 times, carrying a sign that said “Not One More.” She wanted to dramatize the fact that many of the kids Bill grew up with were dying from overdoses of OxyContin or, when they could not afford prescription pills any longer, heroin.

She called us one day crying, begging for help.  Bill had taken so much OxyContin and Xanax the day before that she was sure he was going to die.  We took him in because Purdue Pharma has yet to establish a fund to pay for detoxing and treating dying kids whose families have no financial resources.

A week ago Bill, his mom, and his sister came to Malibu Beach Recovery Center to celebrate his six months of sobriety.  Bill is working full time, physically fit, and zealous about his new life. He truly inspired the clients currently in treatment at the Center. 

The only sad moment was when he told us he had recently attended the funerals of two more childhood friends, both dead from drug overdoses.

 

A Cultural Reflection: The Crimes They Are AChangin'

Los Angeles Civil and Criminal Defense Attorney Mary Masi contributed this interesting article.   Thanks, Mary.mary masi 2.jpg

      The measure of a society is to a degree reflected by how its vulnerable people are treated under the law. In the modern world, society is also measured by the character and prevalence of its crimes and misdemeanors.  Without a doubt, drug and alcohol related crimes are the most prevalent today. 

       Outlaws used to rob banks and railroad cars, but in October 2010 a pharmaceutical truck was robbed and the driver was kidnapped.  The thieves stole only vicodin and OxyContin, a painkiller thought of as synthetic heroin.  The crimes they are a changin’.

      Also in October, 52 people were arrested for organized crime racketeering involving Medicare fraud.  Some of them may face allegations of forged prescription sales involving OxyContin.  Racketeering for prescriptions? This is a cultural wake-up call without a snooze option.

     The modern news is filled with cases similar to those discussed above, and heaven knows our jails and prisons are filled with people who never would have done whatever sent them there had they not been under the influence.  Again, alcohol and drug related crimes and misdemeanors account for approximately 90% of American crimes committed.  How did this happen?

          Since the 1960s pop culture has reflected a degree of “cool” rebellion in the illegal use of drugs and excessive use of alcohol to get high.  Currently, one of the saddest modern trends is the self-imposed choking asphyxiation game.  In Wheat Ridge, Colorado a teenager was criminally charged with reckless endangerment when she performed the choking game on her friend Gabrielle Abuzhars.  What a cultural STOP sign!

         There are healthy alternatives to soothing and stimulating the oversized and often over-active human brain.  For openers, simple exercise works pretty well.   John J Ratey, MD,  Associate Clinical Professor of Psychiatry at Harvard Medical School authored the book “Spark: The Revolutionary New Science of Exercise and the Brain.”  He stated: “Be clear.  My analysis of the findings and testimonies and stories make it clear that exercise can play a huge role in the initial withdrawal, the initial and prolonged dealing with cravings, and offer a substitute activity addiction, like AA to help repopulate the frontal cortex choices of what and how to respond to eventual stressful situations, and losses.”    

           Statistically, Alcoholics Anonymous has the highest success rate in the long-term treatment of alcoholism and addiction.  It would appear to be a no-brainer that exercise and nutrition can play an important treatmentenhancementrole.  There are also other creative alternatives for treatment enhancement.  We as a society clearly need to use our healthy brains to develop more.  It sure would help if some of the alternatives were perceived as “cool.”    So, how exactly does a society make exercise, nutrition, and other healthier alternatives “cooler” than getting high?  How about if a few more rock stars and former bad girls were selected to do some Nike commercials? We can do it - one step at a time.  

 About the Author:

Mary Masi is a Los Angeles Criminal Defense Lawyer specializing in DUI and drug related cases and alternative sentencing.  In 2011, she also won dismissal of all fraud, conspiracy, and racketeering claims valued at over $100 million dollars for her clients in Los Angeles who were greatly relieved.  www.marymasilaw.com 

Kids and Prescription Drug Abuse

child and medicine cabinet.jpgPrescription drug abuse is an epidemic in California and across the U.S.  Easy access to the numerous prescription medications found right in our own medicine cabinets can lead to abuse.   

As the father of three young children, even though I am part of Malibu Beach Recovery Center, I wanted to commend the efforts of our colleagues at the Promises Treatment Centers who recently tried to increase awareness of the prescription pill abuse epidemic with LocktheCabinet, a public awareness campaign. The program was designed educate parents about the need to secure prescription pills at home.

A press release says that addiction usually starts in the teen years, when peer pressure runs high.  It goes on to point out that many teens now believe that taking prescription medications to get high is safer than using illicit drugs because prescription medications are legal and provided by a doctor; however, abusing these drugs can be just as dangerous as using cocaine or heroin.  Those who get hooked on opiate painkillers like OxyContin often start abusing heroin if they find it is easier a nd cheaper to obtain than the prescription medication.

The LocktheCabinet website has information about prescription drug abuse and how to recognize the signs of abuse, and also details how to properly dispose of unused medication. There’s also a Facebook page for parents to share information, make suggestions, and ask questions.

Kids who abuse pills have admitted stealing them from their houses. As the press release stated, a 2008 survey found that “1.9 million teens between the ages of 12 and 17 abused prescription medication, with 1.6 million abusing a prescription painkiller such as Vicodin or OxyContin.” And in many cases, parents unwittingly supplied them.

 

AARP Article on Seniors and Addiction

I know from an article I wrote on alcohol dementia for the Alzheimer’s Foundation Care ADvantage magazine (winter/spring 2010 issue, pg. 17), that when seniors drink excessively, it’s a whole different animal compared to young people drinking. For one thing, older people metabolize alcohol differently from their younger counterparts. In addition, the loved ones who may be in the best position to do something about it may be in denial about the extent of the problem. For example, an adult child might say, “Oh, let Dad have his drinks at night. He’s been grieving about Mom since she passed away.”older alcoholic.jpg

A “special report on older addicts” in a recent edition of AARP magazine quotes a report from SAMHSA as predicting that the “number of boomers with substance-abuse problem will double from 2.5 million in 199 to 5 million in 2020.” The article notes that the need for treatment will also double and blames it the proliferation of prescription medication use.

The article opened with the story of a 52-year-old man who was abusing alcohol and other drugs which devastated his family, including an 8-year-old son. The son becomes so enraged at his father’s drinking that he rips up a photo of the two of them, which propels his father to agree to rehab.

I don’t know about you, but I like having as many facts as possible about addiction, and this author comes through. She notes that doctors have become more aggressive in attempting to treat pain in the last few years, and many pain sufferers have benefitted. However, the pills cause euphoria, which contributes to the problem of addiction. One doctor even prescribed Oxycodone to a 50-year-old who had become addicted to it in the past and told the doctor so.

As Candy Finnegan also pointed out when I interviewed her, the article reminds readers that the intervention industry is not regulated so families have to do their research when selecting an interventionist. Families can contact rehab centers, who can usually recommend professionals, and should also ask anyone they’re thinking of hiring about his or her clinical experience. And even though one family in the article chose to include a young child in an intervention, the author includes a word of caution about doing this.

It’s an interesting—and cautionary—article. Wish I’d written it!

Drug Makers Infiltrating a College Curriculum?

Occasionally drug makers have been devious in their advertising. Several times the government has made them change or pull their ads for making false claims. Or we’ve learned that they’ve funded studies and then neglected to mention, covered up, or glossed over, the negative results when reporting on the research. In December a Canadian news site, CBC News, revealed something similarly outlandish: a drug company that funded a book on managing chronic pain was able to get it in front of medical students in a pain management course.pills.jpg

The culprit? Purdue Pharma, the company that manufactures the painkiller OxyContin.

The book wasn’t actually required reading and it wasn’t distributed by the University of Toronto Medical School. But an unpaid guest lecturer linked to the drug company brought not one book, but several, into the Centre for the Study of Pain, which gave the pain class. The pain curriculum is “a 20-hour course jointly taught to medical, dental, pharmacy and nursing students,” according to the article.

A student and two doctors on the faculty complained after the student alerted the doctors about the book, and the school conducted an informal investigation. (What’s especially sad is that Dr. Rick Glazier, one of the doctors, experienced the tragedy of prescription pill misuse firsthand—his 18-year-old son succumbed to an accidental overdose of OxyContin.) Luckily, their voices were heard:  Lorraine Ferris, associate vice-provost in the department of Health Sciences Policy and Strategy, who headed the investigation advised that the curriculum be revamped to include balanced information and suggested it be done poste-haste.

The other faculty member, Dr. Phillip Berger, said about the inquiry: "She's raised very serious issues of conflict of interest and made what I think is an absolutely correct statement that not only the academic community but the public more generally would find making a copyrighted and owned drug-company textbook available to students objectionable, regardless of how its assessed quality is.” Not only that, but Ferris recommended that the development and accountability for the course be moved out of the Centre that gives the course. Smart idea!

An article on the CTV website, another Canadian news site, noted that the dean of dentistry at the university identified the lecturer as Dr. Roman Jovey, who co-authored the book. Jovey is paid by Purdue to lecture.

This article quoted Dr. Irfan Dhalla, a doctor at a Canadian hospital who also lectures at the University. He had significant concerns about the book. For one, it suggests that it’s fairly safe to prescribe opioids for chronic non-cancer pain, which he believes is untrue. The evidence indicates that it’s appropriate for cancer pain or other severe acute pain, but not non-cancer pain, and it’s a strong drug—twice as strong as morphine, and it is not the moderate one the authors suggest, Dhalla added.

The book also holds that the addiction rate is low for non-cancer pain sufferers—also not true, Dhalla said, and it glosses over the possibility of dying from an overdose. Finally, the doctor raises the issue of medical students being influenced by the misinformation put forth in the book when they become doctors prescribing pain medications. He’s concerned that younger doctors are more liberal with opioids than their predecessors, which points us again to the misinformation in the book.

Jovey said he wasn’t embarrassed or ashamed about what he did.  Imagine.

Addiction by Prescription: The Purdue Pharma-OxyContin Saga Continues

A mom called the other night from Simi Valley, one of L.A.’s bedroom communities.  She was crying, begging for help.  She had been up the previous night with her 22 year old son – we’ll call him Bill.  He was so addicted to OxyContin and Xanax that she would check on him several times each night to make sure he was still breathing.    The night before he was so sick, she was sure he was going to die.Thumbnail image for march flyer.jpg

Her son, she said, has been getting prescriptions from half a dozen local doctors for the past 3 years.  He would show them two folders of medical records he compiled from accidents that occurred several years ago.  They would give him 150- thirty milligram pills per month.

He was crushing and snorting at least five OxyContin each day – more if he could get them.  He once smoked pulverized pills for a short period of time; he had never actually swallowed one.  He did swallow his Xanax – at least 60 each month, all prescribed by the same doctors.  OxyContin and Xanax, by the way, were key ingredients in the lethal cocktail that killed actor Heath Ledger in 2008.

Bill doesn’t drink or use street drugs.  He insists he did not know OxyContin was highly addictive, that the doctors never told him.  Once he understood he started trying to get off prescription drugs by going “cold turkey” because the family did not have enough money to pay for a medically-supervised detox.  He ended up having seizures and putting his parents into panic mode.

Hard to believe that just three years ago U.S. Attorney John Brownlee won a major legal battle in Virginia against Purdue, the privately owned pharmaceutical which manufactures OxyContin. 

“Despite knowing that OxyContin contained high concentrations of oxycodone, had an abuse potential similar to that of morphine, and was at least as addictive as other pain medications on the market, Purdue, beginning in January of 1996, with the intent to defraud and mislead, marketed and promoted OxyContin as less addictive, less subject to abuse and diversion, and less likely to cause tolerance and withdrawal than other pain medications,” Brownlee told PBS Newshour in May 2007.  “Of the $600 million Purdue will pay, $130 million will be used to resolve civil suits brought by patients who say they became addicted to the drug…Over the years, OxyContin has legitimately helped many patients cope with pain, but its criminal abuse has been widespread. The drug has been connected with hundreds of deaths and arrests.”

Dr. Sidney Wolfe of the Public Citizen Health Research Group spoke during the same PBS Newshour.  He said:  “…Someone in the company, it wasn't robots, designed this program to mislead doctors into thinking that this drug was much safer than it was and get them to prescribe it preferentially over other drugs.”

What has changed since then?  Not much.

Bill’s mom earns $10/hour.  Her husband, a chef, is on disability.  He was injured serving relief workers during Katrina.  She told me she could raise enough money to pay something for a doctor, but that was all.  Someone had given her the name of Malibu Beach Recovery Center.   I don’t know why because we are small, boutique and expensive.  Not a good fit.   

Together with our marketer, I called frantically around to find a free or almost free facility where Bill could get detoxed.  He wanted help, but as everyone in this industry knows, an addict’s “window of willingness” is very short.  I told his mom – “We have to move fast.” There was nowhere cheap enough to go except American Hospital in Pomona, which has a 4-7 day waiting list.  

It was getting late.  The mom was calling every few minutes.  She was very frightened.  She was also on Day 22 of a forty day march.  Every evening she walks from one side of Simi Valley to the other -- 10 miles -- to raise awareness for Bill’s plight and that of virtually all of his friends, friends he has had since kindergarten.  They are all, she says, severely addicted to OxyContin -- if they aren’t already dead.  With 28 more days of marching still to go, she had organized a 100 mom “Not One More” Promise Walk for October 9, 2010.  The goal?  Make the mayor and city council members aware of what is happening right under their noses.

It was a just cause.  We’ve already had several young clients from Simi Valley and adjacent Moorpark.  The parents all say the same thing:  They moved to these “Leave It to Beaver” communities from the San Fernando Valley to give their kids better lives.  Instead they became OxyContin addicts. 

We found a way to take Bill in for 7 days and get him detoxed.  Our plan was to then transfer him to one of the long term free treatment programs that do exceptional work but do not provide medically supervised detox services.  Once detoxed he chose instead to move in with a sober friend and work in construction.  He just called to report he is hiking and rock climbing alot; he assured me that when he feels cravings for OxyContin he does some of the yoga breath work he learned from our lead exercise instructor Oleg Yevseyev.  I told him to call if he ever needs help again.

The OxyContin epidemic is not unique to Simi Valley and Moorpark.  Last May I travelled to Sacramento with some of our alumni to support passage of a funding bill for CURES (California’s real time online narcotic prescription data base). The parents who spoke at the press conference were all from one Northern California Senate District, that of Senator Mark DeSaulnier who authored the bill.  All of their children had died from OxyContin overdoses (one of them, April Rovero, went on to found the National Coalition Against Prescription Drug Abuse).

Nine months earlier I had several conversations with Lynette Ropp, a mom who lives in El Dorado County, yet another area of California where young people are dying from their addiction to this powerful drug which many parents describe as nothing more than synthetic heroin.  Matt’s presence at Malibu Beach Recovery Center made me think of her, and her efforts to get Purdue Pharma to pay the costs of getting her son detoxed and treated.

“I continue to watch my son battle with OxyContin addiction. I am totally exhausted,” she wrote to the head of Purdue Pharma. “This past year has been very sad and stressful, checking constantly to make sure he is still breathing...Seeing him with dark circles under his eyes, watching him mumble his words unable to articulate himself clearly at times. So worried he will die.  I called 911 at one point and he was taken by ambulance to the hospital for overdose.  The rehab the doctor referred him to was closed for misappropriation of funds.  He had been attending a outpatient program but slowly that tapered off...A couple weeks ago at a softball game (he plays in a league with long time childhood friends) he was unable to throw a softball 15 feet.  My sister attended the game with her children and reports that he struggled to spit out a piece of gum.  Stumbling and cussing, humiliating himself in front of friends and family.  It is painful to watch my child who was such a talented, vibrant young man be totally depressed and sick...He needs professional medical help.  I believe I have found the appropriate facility.  Unfortunately everything comes down to money. So I find myself again contacting your office asking for help…”

Purdue never did provide the funds Lynette’s son needed to get professional treatment.  Instead he went to jail for 9 months because of multiple legal charges related to his OxyContin habit.  He is now clean and sober thanks to the largesse of California tax payers.

So here’s my question.  We did our part.  But what about the doctors who by now know that OxyContin is highly addictive?   Shouldn’t they have to detox these kids for free?  And what is the responsibility of Purdue Pharma, which manufactures OxyContin and still allows it to be prescribed in such lethal quantities?    Why haven't they set aside a very large fund to help Bill, and Lynette Roup's son, and OxyContin addicts across the country get their lives back?